PEPperPRINT: PEPperCHIP® Peptide Microarray Solutions for Antibody Validation

PEPperCHIP^® Peptide Microarrays: A powerful tool for antibody analysis

Our PEPperCHIP^® Platform Technology allows for the direct synthesis of thousands of peptides on glass slides, enabling high-throughput screening and detailed amino acid-level analysis of antibody interactions at minimal cost. Learn more about the applications of peptide microarrays for anitbody validation.

Epitope Mapping

Epitope mapping is essential for identifying the exact binding sites of antibodies on their target antigens. PEPperCHIP^® Peptide Microarrays allow for epitope identification at the amino acid level, providing detailed insights into antibody-antigen interactions. This information is critical for understanding the molecular basis of antibody specificity, designing effective therapeutics and diagnostic tools, and even protection of intellectual property.

Antibody Cross-Reactivty Analysis

Determining antibody specificity is crucial to avoid off-target effects in both research and clinical settings. PEPperCHIP^® Peptide Microarrays can be used to screen and evaluate the binding of antibodies against a wide range of peptides, identifying potential cross-reactivities. This can ensure that antibodies are highly specific to their intended targets, enhancing the reliability of experimental results and the safety of therapeutic applications.

Epitope Substitution Scan

Epitope substitution scans using PEPperCHIP^® Peptide Microarrays identifies conserved and variable amino acid positions within epitopes. By systematically substituting each amino acid in the epitope with all other amino acids, we determine whihc residues are critical for antibody binding. This information is invaluable for optimizing antibody or therapeautic peptide design and for understanding the structural basis of antigen recognition.

Antigen and Epitope Discovery

PEPperCHIP^® Peptide Microarrays are an ideal tool for antigen and epitope discovery. Thanks to its high density content and scalabililty, we can screen for novel antigens and epitopes across large peptide libraries, facilitating the discovery of new biomarkers and therapuetic targets. This application is ideal for vaccine development, diagnostic assay design, and biomarker identification.

Fully flexible options for every budget

With PEPperCHIP^® Peptide Microarrays, the choice is yours: take full conrol and validate your antibodies at your own facility, or send us your samples and let us do the work for you. Get comprehensive support from our specialists no matter which option you choose.

Unsure about which solution is best suited for you? Get in touch with us for a free project assessment.

	DIY solution	with PEPperMAP^® Service
Project consultation	free	free
Samples for analysis	processed at your facility	shipped to PEPperPRINT
Immunoassay	optional add-on: PEPperCHIP^®Accessories	included
Data acquisition	requires microarray scanner	included
Data analysis	optional add-on: MAPIX Analyzer software	included
Full scientific report	-	included
Dedicated customer support	included	included
	Build your own kit	Choose a service

Read the case studies

Learn more about how we validate antibodies with actual data from some of our internal and customer projects. Visit our Downloads and Resources page to access additional learning materials.